Ihe mgbakwunye nri TianJia Onye nrụpụta Choline chloride
Choline chloride bụ ngwakọta organic nwere usoro kemịkalụ C5H14ClNO.Ọ bụ kristal hygroscopic na-acha ọcha, enweghị isi, ma nwee isi azụ.Ebe mgbaze 305 ℃.Ngwọta mmiri 10% nke nwere pH 5-6 adịghị eguzosi ike na ngwọta alkaline.Ngwaahịa a na-adị mfe mgbaze na mmiri na ethanol, ma ọ bụghị na ether, petroleum ether, benzene, na carbon disulfide.Nsi dị ala, LD50 (oke, ọnụ) 3400 mg / kg.A na-eji ya maka ọgwụgwọ imeju abụba na cirrhosis.A na-ejikwa ya dị ka ihe mgbakwunye nri maka anụ ọkụkọ na anụ ụlọ, ọ nwere ike ime ka ovaries na-emepụtakwu àkwá, ihe mkpofu, na ibu ibu na anụ ọkụkọ, azụ na anụmanụ ndị ọzọ.
Ojiji:ọgwụ, kemịkalụ, ngwaahịa nri, ngwaahịa ugbo, ihe mgbakwunye nri
Dị ka ihe mgbakwunye nri, choline chloride nwere mmetụta physiological ndị a:ọ nwere ike igbochi nchịkọta abụba na mmebi anụ ahụ na imeju na akụrụ;nwere ike kwalite recombination nke amino acid;Ọ nwere ike melite ogo ojiji nke amino acid, ọkachasị amino acid methionine dị mkpa, n'ime ahụ.Na Japan, 98% nke choline chloride na-eji dị ka nri mgbakwunye maka anụmanụ dị ka ọkụkọ, ezi, ehi ehi, na azụ na oporo.Ọtụtụ n'ime ha na-esichara n'ime ntụ ntụ, na nkwadebe usoro maka 50% ntụ ntụ bụ tupu tinye ihe kwesịrị ekwesị urughuru size excipient na igwekota, wee dobe tinye a choline chloride mmiri ngwọta, nke agwakọta na akpọnwụwo.A na-ejikọta ụfọdụ ntụ ntụ ngwaahịa na vitamin, mineral, ọgwụ ndị ọzọ. Choline chloride bụ ọgwụ vitamin B nke a na-eji agwọ ọrịa ndị dị ka ịba ọcha n'anya, mmebi imeju, cirrhosis mmalite, na ọrịa anaemia.
Choline bụ akụkụ dị mkpa nke lecithin, nke na-arụ ọrụ dị mkpa n'ịkwado usoro na ọrụ nkịtị nke membranes cell, yana metabolism lipid, ma nwee ike igbochi ntinye abụba imeju.
Choline bụkwa ihe dị mkpa na njikọ nke neurotransmitter acetylcholine, ọ na-arụkwa ọrụ dị ka onyinye methyl na njikọ nke methionine.
A na-eji Choline chloride maka nkwalite uto na ụkọ choline.
Nri nri nwere ụfọdụ choline, nke nwekwara ike imeju imeju n'ime ahụ, yabụ na ọ naghị akpata ụkọ choline.Otú ọ dị, anụ ọkụkọ pant poteto, karịsịa ụmụ ọkụkọ, nwere nnukwu ọchịchọ maka choline ma nwee obere njikọ.Ọ bụrụ na agbakwunyeghị nri ahụ nke ọma ma ọ bụ jiri nri ọdịnaya choline dị ala (dị ka ọka) rie ogologo oge, ọ dị mfe ime ụkọ.
Mgbe anụ ọkụkọ anụ ụlọ na-arịa ọrịa imeju ma nwee vitamin B2 na folic acid ezughi oke na nri ha, ọ nwekwara ike ịkpata ụkọ choline.Mgbe ụkọ choline na-apụta, ezì na-egosipụta uto nwayọọ nwayọọ, nkwonkwo nkwonkwo na dyskinesia, ntinye abụba imeju, na mbelata ọrụ ọmụmụ.Anụ anụ ọkụkọ na-egosiputa ngwa ngwa ngwa ngwa, tibia dị mkpụmkpụ na nke siri ike, nke na-adịkarị mfe nkwụsị aka, ọrịa imeju nke abụba abụba, na mbelata mmepụta akwa.
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